BIONUMERICS offers phylogenetic tree construction methods such as Maximum Parsimony and Maximum Likelihood. Besides standard algorithms, the optimal trees can be calculated using simulated annealing or quartet puzzling. Both methods result in an unrooted tree, which can be converted into a rooted tree after assignment of a root. To correct phylogenetic distance scaling, the Jukes & Cantor or Kimura 2 parameter correction factors can be chosen.
Supported in BIONUMERICS configurations: